What is Ivermectin 12 mg?
Ivermectin ( Iverheal 12 ) is a broad-spectrum ant parasitic medication. The 12 mg dosage refers to a higher strength of the drug, typically prescribed for more severe infections or when a higher dose is required for treatment. It is widely used for both humans and animals and is classified under the anthelmintic drug category, primarily targeting parasites such as worms, lice, and mites.
How Does Ivermectin Work?
Ivermectin works by interfering with the nerve and muscle function of parasites. It binds selectively to specific chloride ion channels found in the nerve and muscle cells of invertebrates, causing increased permeability of the cell membrane to chloride ions. This results in paralysis and death of the parasite, thereby eliminating the infection.
Buy Ivermectin for humans
Human cells lack these specific channels, making Ivermectin safe and effective when used in appropriate dosages.
Uses of Ivermectin 12 mg
- Human Uses: Ivermectin is approved and widely used to treat several parasitic infections in humans, including:
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- Onchocerciasis (River Blindness): Caused by the parasitic worm Onchocerca volvulus.
- Strongyloidiasis: An intestinal infection caused by Strongyloides stercoralis.
- Scabies: A skin condition caused by the Sarcoptes scabiei mite.
- Head Lice: An infestation caused by Pediculus humanus capitis.
- Lymphatic Filariasis: Caused by filarial worms, often in combination with other drugs.
Off-label uses (not FDA-approved but sometimes prescribed by healthcare providers):
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- Rosacea (inflammatory skin condition).
- Treatment of certain protozoan infections.
- Experimental uses in some viral conditions (e.g., COVID-19, though efficacy in this context is controversial and not officially recommended).
- Veterinary Uses: Ivermectin is widely used in veterinary medicine for the treatment of parasitic infections in animals, such as:
- Heartworms in dogs.
- Intestinal worms in livestock (e.g., cattle, sheep, goats).
- Mites and lice infestations in various animals.
Dosage and Administration
- Formulations: Ivermectin is available in various forms, including tablets (3 mg, 6 mg, 12 mg), topical creams, and injectables.
- Dosage for Humans: The recommended dosage depends on the type and severity of the infection:
- Strongyloidiasis: Typically, a single dose of 200 mcg/kg of body weight.
- Onchocerciasis: A single dose of 150 mcg/kg, repeated every 6–12 months.
- Scabies or Lice: Often given as 200 mcg/kg, with a follow-up dose in 1–2 weeks.
For a 12 mg tablet, the dosage is calculated based on body weight, ensuring the patient receives the correct amount.
Note: Always follow your doctor’s prescription, as self-dosing can lead to severe side effects.
Precautions and Warnings
- Allergies: Inform your doctor if you are allergic to Ivermectin or any of its ingredients.
- Medical Conditions: Ivermectin should be used cautiously in individuals with liver disease, kidney problems, or those with a weakened immune system.
- Pregnancy and Breastfeeding: The use of Ivermectin in pregnancy is generally avoided unless absolutely necessary. It may also pass into breast milk.
- Drug Interactions: Avoid taking Ivermectin with certain medications (e.g., sedatives, barbiturates, benzodiazepines) that affect the central nervous system. Inform your doctor of all medications and supplements you are taking.
Possible Side Effects
While Ivermectin is generally well-tolerated, some people may experience side effects, including:
- Common Side Effects:
- Nausea or vomiting
- Diarrhea
- Dizziness
- Fatigue
- Skin rash or itching (mild allergic reaction)
- Serious Side Effects:
- Severe skin reactions or rashes
- Vision changes
- Swelling or difficulty breathing (signs of an allergic reaction)
- Neurological symptoms such as confusion, seizures, or loss of consciousness
- Liver function abnormalities (rare)
- Mazzotti Reaction: In people treated for onchocerciasis, Ivermectin can cause a “Mazzotti reaction,” which includes fever, swelling, and a severe allergic-like response due to the death of parasites.
Seek immediate medical attention if any serious side effects occur.
Overdose and Toxicity
Taking higher-than-prescribed doses of Ivermectin can lead to toxicity. Symptoms of overdose include:
- Severe nausea or vomiting
- Tremors or seizures
- Difficulty breathing
- Loss of coordination
If an overdose is suspected, seek emergency medical care immediately.
Controversies and Misuse
Ivermectin gained widespread attention during the COVID-19 pandemic when it was touted by some as a potential treatment for the virus. However:
- The World Health Organization (WHO) and U.S. FDA have stated that there is insufficient evidence to recommend its use for COVID-19.
- Large studies have shown little to no benefit in treating or preventing COVID-19 with Ivermectin, and its use for this purpose is not officially approved.
Misuse of Ivermectin, especially veterinary formulations intended for animals, can lead to severe adverse effects in humans.
Availability and Pricing
Ivermectin 12 mg is available globally under various brand names, such as:
- Stromectol (by Merck)
- Iverheal, Ivecop, and Iverjohn (generic brands)
Prices vary depending on location, formulation, and manufacturer. Generic versions tend to be more affordable.
Storage and Handling
- Store at room temperature (15–30°C or 59–86°F).
- Keep away from moisture, heat, and direct sunlight.
- Keep out of reach of children and pets.
Conclusion
Ivermectin 12 mg is a powerful antiparasitic medication that has transformed the treatment of many parasitic infections. When used correctly under medical supervision, it is effective and generally safe. However, like all medications, it must be taken cautiously, as misuse or inappropriate dosing can lead to serious side effects or toxicity. Always consult a healthcare provider before starting or stopping Ivermectin.
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